14/05/2026
1979 - Palestra de encerramento de Albert Sabin no Comuabc
03/05/2026
Propagandas de "medicamentos" da época pré-científica da medicina
04/04/2026
CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat Sickle Cell Disease
CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat Sickle Cell Disease | NEJM
Renizgamglogene autogedtemcel (reni-cel) is an investigational clustered regularly interspaced short palindromic repeats (CRISPR)–Cas12a gene-edited autologous hematopoietic stem-cell therapy. The ...
17/02/2026
Sacubitril/Valsartan vs Enalapril in Heart Failure Due to Chagas Disease - An Open-Label, Multicenter Randomized Clinical Trial
Sacubitril/Valsartan vs Enalapril in Heart Failure Due to Chagas Disease
This randomized clinical trial examines the safety and efficacy of guideline-recommended treatments for patients with heart failure with reduced ejection fraction caused by Chagas disease.
15/02/2026
The gut-lung axis in COPD: immunomodulatory roles of gut microbiota and novel therapeutic strategies
https://pmc.ncbi.nlm.nih.gov/articles/PMC12886472/?fbclid=IwdGRleAP_B0JleHRuA2FlbQIxMQBzcnRjBmFwcF9pZAo2NjI4NTY4Mzc5AAEeBGWD5N1ayh6c0qF2f6wKKROjxq2tPRJLZh0JF530yMpoeoQ3_lW-xMiraN4_aem_SE6ixgjHaPA95Y3QsOjibQ
The gut-lung axis in COPD: immunomodulatory roles of gut microbiota and novel therapeutic strategies
Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and systemic inflammation, with accumulating evidence implicating gut microbiota dysbiosis as a key modulator of ...
06/02/2026
Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER) in the UK: a cluster-randomised controlled implementation trial
Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER) in the UK: a cluster-randomised controlled implementation trial
Implementation of an AI stethoscope in routine primary care did not significantly increase detection of heart failure or increase community-based diagnosis after 12 months of implementation. AI stethoscope use was independently associated with significantly higher detection rates of heart failure, a...
25/01/2026
Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
Impact of commonly used drugs on the composition and metabolic function of the gut microbiota - Nature Communications
Here, via a metagenomics analysis of population-based and disease cohorts, Vich Vila et al. study the impact of 41 commonly used medications on the taxonomic structures, metabolic potential and resistome of the gut microbiome, underscoring the importance of correcting for multiple drug use in m...
03/01/2026
FDA approved drugs in 2025