Developmental Cognitive Neuroscience Lab

Semana Acadêmica Integrada PUCRS 2025!

Na próxima terça-feira, 28/10, às 19h30, nossa doutoranda estará participando da Semana Acadêmica Integrada da PUCRS, a convite da Escola de Ciências da Saude e da Vida com a palestra:
“Aptidão Física e Cognição em Escolares”

Será uma conversa sobre como o movimento e o desenvolvimento cognitivo se conectam e por que essa relação é fundamental para o aprendizado e a saúde das crianças. 🧠🤸🏻‍♀️

📍 Local: Prédio 81, 5º andar
🔗 Inscrições disponíveis no link da bio do

Processo Seletivo Aberto!

Inscrições e Edital no link abaixo:

https://linktr.ee/DCNL

👍👌

New publication in Neuroscience Letters by Rodrigo Grassi-Oliveria's research team In collaboration with their colleagues from Brazil, TNU researchers Rodrigo Grassi-Oliveira and Rodrigo Orso have just published the article

Parabéns Lucca e equipe, mais que merecido! O trabalho “ Semelhanças entre o envelhecimento fisiológico e a atrofia cortical relacionada ao uso de Crack- Cocaína” ganhou o prêmio CCM de incentivo à pesquisa no Congresso Brain Behavior and Emotions!

https://inscer.pucrs.br/br/artigo-do-inscer-e-publicado-em-revista-do-grupo-nature

Artigo do InsCer é publicado em revista do grupo Nature - Inscer Acaba de ser publicado na prestigiada revista internacional Translational Psychiatry, que faz parte do grupo Nature, artigo conduzido pelo pesquisador...

High expected probability of running out of money is positively associated with mental health score, while perceived risks of dying from Covid-19 and social are also strongly correlated with higher levels of depression/anxiety. Therefore, as the number of cases continues to rise, public-health politics may consider not only sensitizing people regarding infection rates, but also by providing health information and services, financial incentives, or fiscal alternatives so that people can maintain their businesses in a sustainable way. Our findings add to the political and public debate concerning lockdown strategies by showing that, contrary to supposition, people with low socioeconomic status are not more likely to ignore social distancing recommendations due to personal economic matters.

A behavioral economic risk aversion experiment in the context of the COVID-19 pandemic We investigated what degree of risk of infection with COVID-19 is necessary so that people intend to stay home, even when doing so means losing their salary. We conducted an online survey across Brazil during the initial outbreak, in which 8,345 participants answered a questionnaire designed to iden...

Prêmio SIC 2020 da Grande Área Ciências Humanas!!! 😁Parabéns ao nosso querido Leozinho!!!

Pesquisador do InsCer é contemplado em edital da Fundação Bill & Melinda Gates - Inscer | Instituto do Cérebro Thiago Wendt Viola trabalhará em projeto que analisará aspectos variados no tratamento de desintoxicação para mulheres usuárias de co***na e crack

Nosso Lab está muito feliz pelo sucesso do nosso querido co-líder Thiago Viola na conquista de um edital de tamanho vulto e impacto como o Bill & Melinda Gates/MS/CNPq!! Foram várias etapas e poucos projetos aprovados, então isso da muito orgulho para todos nós!!!

Maternal Separation Combined With Limited Bedding Increases Anxiety-Like Behavior and Alters Hypothalamic-Pituitary-Adrenal Axis Function of Male BALB/cJ Mice

Early life stress (ELS) is considered a risk factor for the development of psychiatric conditions, including depression and anxiety disorder. Individuals that live in adverse environments are usually exposed to multiple stressors simultaneously, such as maternal neglect, maltreatment, and limited resources. Nevertheless, most pre-clinical ELS models are designed to explore the impact of these events separately. For this reason, this study aims to investigate the effects of a combined model of ELS on anxiety-like behavior and hypothalamic-pituitary-adrenal (HPA) axis related targets. From PND 2 to PND 15 BALB/cJ mice were exposed simultaneously to maternal separation (MS; 3 h per day) and limited bedding (LB; ELS group) or left undisturbed (CT group). Maternal behavior was recorded in intercalated days, from PND 1 to PND 9. Male offspring were tested for anxiety-like behavior from PND 53 to PND 55 in the open field test (OF), elevated plus-maze (EPM), and light/dark test (LD). After behavioral testing, animals were euthanized, and glucocorticoid receptor (Nr3c1), corticotrophin-releasing hormone (Crh), and its receptor type 1 (Crhr1) gene expression in the hypothalamus were measured. Moreover, plasma corticosterone levels were analyzed. We observed that ELS dams presented altered quality of maternal care, characterized by a decrease in arched-back nursing, and an increase in passive nursing. Stressed dams also showed an increase in the number of exits from the nest when compared to CT dams. Furthermore, ELS animals showed increased anxiety-like behavior in the OF, EPM, and LD. Regarding gene expression, we identified an increase in hypothalamus Crh levels of ELS group when compared to CT animals, while no differences in Nr3c1 and Crhr1 expression were observed. Finally, stressed animals showed decreased levels of plasma corticosterone when compared to the CT group. In conclusion, we observed an alteration in maternal behavior in ELS dams. Later in life, animals exposed to the combined model of ELS showed increased levels of anxiety-like behavior. Moreover, the central and peripheral HPA measures observed could indicate a dysregulation in HPA function provoked by ELS exposure.

Maternal Separation Combined With Limited Bedding Increases Anxiety-Like Behavior and Alters Hypothalamic-Pituitary-Adrenal Axis Function of Male BALB/cJ Mice Early life stress (ELS) is considered a risk factor for the development of psychiatric conditions, including depression and anxiety disorder. Individuals that live in adverse environments are usually exposed to multiple stressors simultaneously, such as maternal neglect, maltreatment, and limited re...

Parabéns a todos envolvidos!!!!

Lucca Tondo e Francisco Sindermann Lumertz 👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼

Alunos de Iniciação Científica ganham prêmio nacional com pesquisas feitas no InsCer - Inscer | Instituto do Cérebro Os acadêmicos de iniciação científica Francisco Lumertz e Lucca Pizzato Tondo foram dois dos sete premiados com o Prêmio Jovem Neurocientista Raymundo Francisco Bernardes, da Sociedade Brasileira de Neurociências e Comportamento (SBNEC), a mais importante sociedade científica da área do paí...