Biotech Bee

27/12/2025

Genome editing platforms and DSB repair mechanism👇
✅Timeline of Gene Editing Development
The field of genome editing has rapidly evolved over the years, with new tools and technologies emerging to precisely modify DNA sequences.
✅Genome Editing Technologies
Several genome editing platforms are currently in use:
🔴Meganucleases – naturally occurring enzymes that recognize long DNA sequences.
🔴ZFN (Zinc Finger Nuclease) – engineered proteins that target specific DNA sequences for cleavage.
🔴TALEN (Transcription Activator-Like Effector Nuclease) – customizable proteins that bind specific DNA regions.
🔴CRISPR-Cas9 – a highly versatile system using RNA guides to direct the Cas9 nuclease to specific DNA sequences.
✅DSB Repair Mechanisms
Genome editing introduces double-strand breaks (DSBs) in DNA, which are repaired by the cell through two main pathways:
🔴Non-Homologous End Joining (NHEJ) – directly joins the broken DNA ends, often causing insertions or deletions (indels).
🔴Homology-Directed Repair (HDR) – uses a donor DNA template to precisely replace or insert DNA sequences.
✅Key Abbreviations
NHEJ – Non-Homologous End Joining
HDR – Homology-Directed Repair
💡 https://www.cell.com/.../fulltext/S2162-2531(25)00287-2

Credit: Cancer Biology Research

18/12/2025

Link: https://pharmacy.mercer.edu/hasan-lab/

30/11/2025

29/11/2025

/ Student – / / / 🎓 Exciting PhD/Postdoc opportunity in Europe ( ) for aspiring researchers!
📍 : Europe,
🗓️ Application : 11 January 2026
💼 Type: Full-time
🎓 : Master’s degree in Molecular Biology, Biochemistry, Microbiology, or Computational Science

✨ :
✨ Conduct cutting-edge research in and
🏫 Join a dynamic and collaborative environment
📈 Excellent career development and exposure
https://lnkd.in/d64hvUmA



Source: LinkedIn

26/11/2025

Google Scholar just added a new feature called Scholar Labs, an AI-powered way to search academic papers. This makes finding the right research so much faster and easier. We can now explore topics, summaries, and related works with less time and more accuracy.
AI is really changing the way we learn, write, and discover new knowledge. Exciting times for researchers!

গুগল স্কলার এখন Scholar Labs নামে নতুন AI-চালিত সার্চ ফিচার যুক্ত করেছে। এখন গবেষণার পেপার খোঁজা আরও দ্রুত, সহজ এবং নির্ভুল হবে। খুব অল্প সময়ে আমরা রিলেটেড কাজ, সারাংশ এবং গুরুত্বপূর্ণ তথ্য খুঁজে পেতে পারবো।
গবেষণায় AI সত্যিই একটি বড় পরিবর্তন আনছে—শেখা, লেখা আর নতুন জ্ঞান খোঁজার পথ আরও সহজ হয়ে যাচ্ছে।

22/11/2025

Great opportunities for post doctoral fellow position.