21/06/2022
Chattagram International Dental College-CIDC-14th Batch
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21/06/2022
09/08/2020
đĢ PARKINSON'S DISEASE đĢ
đParkinson's disease is a progressive nervous system disorder that affects movement.
đ Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand.
đ Tremors are common, but the disorder also commonly causes stiffness or slowing of movement.
đĨThe Stages of Parkinson's:
đUncontrollable shaking and tremors.
đSlowed movement (bradykinesia)
đBalance difficulties and eventual problems standing up.
đStiffness in limbs.
đĨ Signs and Symptoms :
đEarly signs
Here are some early signs of Parkinsonâs disease:
đ Movement:
There may be a tremor in the hands.
đCoordination: A reduced sense of coordination and balance can cause people to drop items they are holding. They may be more likely to fall.
đGait: The personâs posture may change, so that they lean forward slightly, as if they were hurrying. They may also develop a shuffling gait.
đFacial expression: This can become fixed, due to changes in the nerves that control facial muscles.
đVoice: There may be a tremor in the voice, or the person may speak more softly than before.
đHandwriting: This may become more cramped and smaller.
đSense of smell: A loss of sense of smell can be an early sign.
đSleep problems: These are a feature of Parkinsonâs, and they may be an early sign. Restless legs may contribute to this.
đ Other common symptoms include:
đ Mood changes
đDepression
đDifficulty chewing
đSwallowing
đProblems with urination
đConstipation
đSkin problems
đSleep problems
đĨCauses and risk factors :
đ Low dopamine levels:
Dopamine plays a role in sending messages to the part of the brain that controls movement and coordination. Low dopamine levels can make it harder for people to control their movements.
As dopamine levels fall in a person with Parkinsonâs disease, their symptoms gradually become more severe.
đ Low norepinephrine levels:
Norepinephrine, another neurotransmitter, is important for controlling many automatic body functions, such as the circulation of the blood.
In Parkinsonâs disease, the nerve endings that produce this neurotransmitter die. This may explain why people with Parkinsonâs disease experience not only movement problems but also fatigue, constipation, and orthostatic hypotension, when blood pressure changes on standing up, leading to light-headedness.
đ Lewy bodies:
A person with Parkinsonâs disease may have clumps of protein in their brain known as Lewy bodies. Lewy body dementia is a different condition, but it has links with Parkinsonâs disease.
đ Genetic factors:
Sometimes, Parkinsonâs disease appears to run in families, but it is not always hereditary. Researchers are trying to identify specific genetic factors that may lead to Parkinsonâs disease, but it appears that not one but a number of factors are responsible.
For this reason, they suspect that a combination for genetic and environmental factors may lead to the condition.
Possible environmental factors could include exposure to toxins, such as pesticides, solvents, metals, and other pollutants.
đ Autoimmune factors:
Scientists reported in JAMA in 2017 that they had found evidence of a possible genetic link between Parkinsonâs disease and autoimmune conditions, such as rheumatoid arthritis.
In 2018, researchers investigating health records in Taiwan found that people with autoimmune rheumatic diseases (ARD) had a 1.37-higher chance of also having Parkinsonâs disease than people without ARD.
đĨ Treatment :
đLevodopa
The most effective Parkinson's disease medication, is a natural chemical that passes into your brain and is converted to dopamine. Levodopa is combined with carbidopa (Lodosyn), which protects levodopa from early conversion to dopamine outside your brain.
đĨ Life expectancy :
đAccording to research, on average, people with Parkinson's can expect to live almost as long as those who don't have the disorder. While the disease itself isn't fatal, related complications can reduce life expectancy by 1 to 2 years.
28/01/2020
1st-6th February â¤ī¸
Sports Week of CIDC AND CIMCđ¤
03/12/2019
Farewell of Microbiology Department â¤ī¸
Best Of Luck to Our Teachers Who are achieved BCSđ¤
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19/02/2019
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Happy New YearâĨ
07/12/2018
BDS 14Th batch...
with respective Our All legend Teachers âŖ
15/06/2018
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A msg from biochemistry department!!!!
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best of luck for pre-card!!
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