07/29/2024
A little red (map2), white (dapi), and blue (gfap) to celebrate on this .
AxoSim
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AxoSim empowers advancements in human neuroscience and accelerates the drug development
AxoSim’s NerveSim® and BrainSim® technology is revolutionizing drug development by offering the CRO industry’s most advanced, clinically-relevant models of neural tissue. The Company developed a 3D cell-based platform that looks and acts like a real nerve, serving as an alternative to costly animal testing and ineffective 2D models. AxoSim’s services provide pharmaceutical companies with high cont
07/26/2024
Athletes are known for their strength and speed, but to compete at an elite level, their brains must connect with their bodies to enable precise motor function.
AxoSim wishes athletes across the globe a safe, meaningful, and victorious Olympics.
Pictured: Our creative take on the Olympic rings using immunofluorescent neurons of our brain organoids
07/25/2024
It was an honor to present yesterday at . If you missed the presentation or want to learn more about AxoSim, stop by our booth to see Megan Terral and Amit Johal.
07/01/2024
AxoSim's BrainSim® spheroids are differentiated for 84 days total. BrainSim® spheroids exhibit markers from neurons (MAP2), astrocytes (GFAP), and oligodendrocyte lineages (Olig2); major cellular components of the human brain.
06/25/2024
For those who weren't able to attend or would like more time to evaluate the data, we have made our posters from the MPS World Summit available on our website: https://buff.ly/3VXInUU
06/24/2024
Brightfield images of NerveSim® before (DIV43) and after (DIV50) dosing with 100 nM Vincristine. A dose range was performed, yielding quantifiable nerve fiber degeneration to produce an IC50 for the three image analysis metrics below.
Molecular Devices LLC
06/20/2024
Meet AxoSim in Montreal for the Peripheral Nerve Society annual meeting. Tyler Rodriguez, PhD will present on Monday at 5:30 PM (O 418).
06/17/2024
AxoSim's microBrain™ organoids can be used to simulate various neurodevelopmental and degenerative diseases. Here, we've grown organoids using iPSCs from a healthy donor (Control) and those of a patient with CDKL5 Deficiency Disorder (CDKL5 KO). While neurons (green) and astrocytes (magenta) develop normally, the CDD organoids show a dramatic hyperactivity phenotype that can be measured via high throughput calcium imaging.
06/11/2024
We are pleased to announce the appointment of Alif Saleh as AxoSim’s new chief executive officer. Founder and current CEO Lowry Curley, PhD, will step into the chief scientific officer role to lead all R&D efforts.
Read more about Alif's appointment and Lowry's new role: https://buff.ly/4aRbayw
06/07/2024
Join AxoSim scientist Corey Rountree for an oral presentation at MPS, "Human NerveSim® is a Peripheral Nerve Model for High-Throughput Functional Neurotoxicity and Neuroprotection Assays."
The presentation will take place on Friday, June 14, 2024, from 11:00 AM to 1:00 PM. Learn more: https://buff.ly/4dUx32J
06/06/2024
Next week at MPS, AxoSim scientist Nicholas Coungeris will present "Identification of a potential therapeutic compound for Rett syndrome using a highly homogenous human iPSC-derived cortical organoid screening platform." Stop by to see Nick at Poster #290 on Thursday, June 13, from 10:00 to 11:30 a.m.
Learn more: https://buff.ly/4dUx32J
06/05/2024
In one week, AxoSim scientist Lise Harbom will present "Modulation of glial differentiation in a 3D iPSC-derived CNS model" at MPS. Visit Lise at Poster #100 on Tuesday, June 11, 2024, from 4:30 PM to 6:00 PM.
Learn more: https://buff.ly/4dUx32J
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