The Ohio State University Clinical and Translational Science Institute

From parachuting action figures to developing a novel method to deliver gene therapy, Dr. Thomas Mendel’s journey is nothing short of inspiring. As one of our Path to K Scholars, his career was jumpstarted through mentorship, funding and protected research time. Now, he’s leading breakthroughs at Ohio State that could reverse childhood blindness. We’re proud to have supported his path to impact!

Retina surgeon works toward cures An eye surgeon divides time between operating room, clinic and gene therapy lab, working toward cures for the diseases he treats.

A new study reveals that patients with type 2 diabetes face significantly higher out-of-pocket costs, especially when complications arise. These financial burdens can lead to skipped treatments, delayed care and worsening health outcomes. Learn more about this study:

The financial toll on patients with type 2 diabetes Cäzilia Loibl’s study uses unique dataset to show worse economic outcomes.

New research led by CTSI director, Julie Johnson, PharmD, explores how genetic testing can personalize and improve pain management. Learn how this research is paving the way for smarter and personalized pain care: https://bit.ly/4m2aYSO

Improving Pain Management with Genetic Testing A new study is providing insights into why some patients experience inadequate relief from commonly used pain medications. Led by Julie Johnson, PharmD, CTSI director and PI and professor of Internal Medicine, and Noor Nahid, PhD, a postdoctoral associate of Biomedical Informatics, researchers found...

More exciting news about heart health! Researchers believe they have found a way to slow down the aging of the heart, and it starts with brown fat. Read More:

Ohio State research may have cracked key to help heart health COLUMBUS, Ohio (WCMH) — Ohio State University researchers believe they have found a way to slow down the aging of the heart, and it starts with brown fat.  Most times when people think o…

More than 4,200 Buckeyes united at the Central Ohio Heart Walk this past weekend to champion heart health and raise vital funds for life-saving science and research. A powerful show of community and commitment. ❤️

2025 Central Ohio Heart Walk: Team Ohio State - Heart Walk - American Heart Association The Heart Walk is the American Heart Association's premiere event for raising funds to save lives from USA's #1 and #5 killers - heart disease and stroke.

A new study published in Gastroenterology shows that an AI tool outperforms traditional methods in predicting mortality risk for hospitalized cirrhosis patients. https://bit.ly/4friEMo

gastro.org

Through participatory programs and state-wide partnerships, we are transforming how communities engage, contribute and benefit from research and scientific discovery. Read More about some of our community partnerships and programs! https://ctsi.osu.edu/news/ohio-state-ctsi-community-engagement-hub-spotlight

Ohio State researchers are testing a new immunotherapy for metastatic breast cancer using modified NK cells to supercharge the immune system. Two patients at are the first in the world to receive it. https://bit.ly/455gcb4

Researcher creates new immunotherapy for breast cancer Patients are the first to enroll in a clinical trial testing a new immunotherapy combination for metastatic breast cancer.

Struggling with a lost sense of smell? Researchers at Ohio State are pioneering new smell aids to help treat anosmia.

New solution on the way for loss of smell scientists are first in the world to test a new, non-invasive treatment for loss of smell. It’s a big step for a condition that currently has no effective treatment.

Early-career investigators can focus on critical cancer research thanks to the Pelotonia Scholars Program, which provides the support and resources needed to jumpstart their careers.

Pelotonia Empowers Future Cancer Researchers The Pelotonia Scholars Program is fueling the next generation of cancer researchers, providing hands-on opportunities and vital support so young researchers can focus on breakthroughs that improve patients’ lives and inspire hope for the future of cancer care.

Ohio State researchers are using 2 novel devices to help baby corals survive. Combining special underwater lighting + 3D printed habitats, survival rates have doubled. This could reshape how we protect vulnerable reef ecosystems. https://bit.ly/45pWEgE

Blending technologies may help coral offspring blossom Coral restoration efforts could be dramatically improved with technologies that support the survival and growth of baby corals, suggests a new study. Findings showed that two novel devices, the Underwater Zooplankton Enhancement Light Array (UZELA) and 3D printed artificial settlement modules, coul...

A promising new cancer drug developed by Ohio State researchers is now being tested in patients. This drug offering hope for those with limited treatment options.

New cancer drug developed at Ohio State in clinical trial For the first time, a cancer drug created entirely at Ohio State is being tested in a clinical trial. It took years of science and teamwork to bring the drug from the lab to reality. Learn how it was developed and how it may offer hope for people with some of the most difficult cancers...