Institute for Bioinformatics Research & Education
08/13/2023
Bioinformatics Hackathon 2023 results presentations are already live:
Bioinformatics and Biostatistics Hackathon 2023 | Project results presentation This is a live stream from Yerevan, Armenia, where the participants of the Bioinformatis and Biostatistics Hakaathon 2023 will present the results of their 4...
06/22/2023
Today, June 22 at 18:00 CET, is our third Bioinformatics Club online meeting dedicated to the discussion of virtual environments and their usage in bioinformatics.
Details:
IBRE Bioinformatics Club Seminars dedicated to discussing bioinformatics
06/14/2023
Last chance to register for the Bioinformatics Hackathon till June 15:
06/06/2023
The Bioinformatics Discussion Club's second meeting is this Thursday, June 8 at 18:00 CET. Join us as we discuss "Pipeline development: Nextflow, Snakemake, or bash?". If you haven't registered yet, please follow the instructions on https://bioinf.institute/bioinfoclub. We can't wait to see you there!
06/02/2023
The recording of the first meeting of the Bioinformatics Discussion Club is now available at: https://www.youtube.com/watch?v=_qS5bCT48xU
Mark your calendars for the next meeting, which will take place on June 8 at 18:00 CET. Don't miss out and be sure to register if you haven't done so already: https://bioinf.institute/bioinfoclub
Bioinformatics Club | 25.05 - Best practices for data sharing This is a recording of the first meeting of the IBRE Bioinformatics Club which took place at 25 May 2023. During this meeting, we discussed platforms and met...
05/15/2023
We are excited to announce the first online session of the IBRE Bioinformatics Club!
Bioinformatics Club is a series of online meetings dedicated to the discussion of key topics of modern computational biology and bioinformatics. Our goal is to provide a platform for both skilled bioinformaticians and newcomers to talk about best practices in data analysis and interpretation of results.
During the first session, we will discuss methods for efficient and reproducible research, including construction of bioinformatic pipelines, environments, documentation, and much more!
Meetings will be held online via Zoom every two weeks on Thursday evenings at 6 pm CET. The first meeting is scheduled for 25 May 2023. To attend the seminars, please register:
IBRE Bioinformatics Club Seminars dedicated to discussing bioinformatics
05/04/2023
We're pleased to announce the release of our first preprint on bioRxiv, which can be accessed at https://www.biorxiv.org/content/10.1101/2023.04.28.538608v1
The work continues our recent efforts to find an optimal strategy for NGS data analysis in medical genetics. Following up on our analysis of pipelines for variant calling (read our previous work at https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-022-08365-3), we present an analysis of the impact of adapters on the accuracy of genetic variant identification.
Our findings indicate that many commonly used methods, such as DeepVariant or GATK-HC, do not show any significant dependence on adapter removal. However, some of the machine learning-based tools show greater sensitivity to the presence of adapters.
Based on our results, we suggest that adapter trimming is not necessary when calling germline short variants in single-sample mode. However, data preprocessing has to be carefully considered when building predictive models for bioinformatics.
Negligible effects of read trimming on the accuracy of germline short variant calling in the human genome Next generation sequencing (NGS) has become a standard tool in the molecular diagnostics of Mendelian disease, and the precision of such diagnostics is greatly affected by the accuracy of variant calling from sequencing data. Recently, we have made a comprehensive evaluation of the performance of mu...
05/02/2023
Exciting news! The Institute of Bioinformatics Research and Education (IBRE) is thrilled to announce its first event, the Bioinformatics Hackathon'2023!
The hackathon will take place in Yerevan, Armenia from 11-13 August 2023. We welcome programmers, biologists, medical doctors, and mathematicians with a keen interest in bioinformatics and biostatistics to join us.
During the 48-hour event, participants will have the opportunity to collaborate with their teams and solve real challenges in biological data analysis.
Apply by June 15 at https://bioinf.institute/hack. See you in Yerevan!