Biosuccess Biotech

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12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs 14/03/2019

Since 1915, PNAS is the official journal of the National Academy of Sciences. It is the second most cited scientific journal, with more than 1.9 million cumulative citations from 2008-2018.

12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs Fifty-two patients with solid tumors had depressed white blood cell and neutrophil counts because of prior treatment with cytotoxic cancer chemotherapeutic drugs. These patients were given one or more i.v. infusions of 0.125–0.25 mg of 12-O-tetradecanoylphorbol-13-acetate (TPA), and this treatment...

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