Department of Genetics Hazara university mansehra

Congratulations sir Sajid Ul Ghafoor and

A Titan collision may link Saturn’s tilt, its moon Hyperion and its rings
https://www.sciencenews.org/article/titan-collision-saturn-moon-rings

The master switch that determines male development is slowly fading.
Over the last 300 million years, the Y chromosome has shed most of the genes it once carried—leaving scientists wondering whether it may disappear entirely in the far future.

Some evolutionary biologists warn that the trend could continue until the Y is gone. Others say it has stabilized and reached a point of balance, with no further loss expected.

The twist?
Several species—such as certain rodents—have already lost their Y chromosome and smoothly evolved brand-new mechanisms to determine s*x. Nature didn’t collapse.
Life merely rewired itself, proving that evolution always finds a blueprint.

Nature Biotechnology's 2025 research review highlights significant advancements in biotechnology, including CRISPR-based gene editing, immunotherapy
- *In Vivo Cell Therapies*: Researchers have developed in vivo strategies for chimeric antigen receptor T cell therapies, using targeted lipid nanoparticles for mRNA delivery to specific T cell subsets.
- *Genome Editing*: Novel genome-editing systems, such as retrotransposons and bridge recombinases, have shown promise for large-scale genome engineering.
- *Base Editing for Rare Diseases*: A customized lipid-nanoparticle-delivered base-editing therapy has been developed for CPS1 deficiency, a rare metabolic disease.
- *Quantum Computing in Drug Discovery*: Quantum generative models have been combined with classical drug-discovery approaches to generate compounds targeting the KRAS protein.
- *AI in Research*: Agentic AI systems are streamlining workflows, reducing human effort, and accelerating research pace.

These advancements showcase the rapid progress in biotechnology, with potential applications in treating various diseases ¹ ² ³.

Would you like to know more about:
1. How CRISPR technology is being applied in cancer treatment?
2. The role of AI in accelerating biotech research and discoveries?

Nature Biotechnology Nature Biotechnology is a monthly journal publishing new concepts in biological technology of relevance to bioengineering, medicine, energy, agriculture, food ...

Admissions open fall 2025

Nature Reviews Bioengineering: Vibration can be applied to cells in vitro and in vivo to trigger specific mechanotransductive pathways and guide cell-fate decisions. This Review explores the use of vibrational stimulation for cell engineering, outlining key pathways, devices and applications for this new mechanical cell-stimulation tool.

Link to the Review in the comments.

Alumni
2014 _ 2018

A new ‘mini-CRISPR’ flexes its editing power in monkey muscles The downsized DNA-slicing machinery may reach more tissues to take aim at more diseases

A new generation of cancer-preventing vaccines could wipe out tumors before they form.

Learn more on : https://scim.ag/40AqlsE

Nature Reviews Genetics: Circular RNAs have gained attention for their stability, immunological advantages and regulatory functions. This Review discusses the therapeutic prospects of circular RNA-based approaches and the emerging role of circular RNAs as biomarkers in disease.

Link to the Review in the comments.