27/08/2026
CASE SUMMARY
Name: ABC Age/Sex: 47 years / Male Occupation: Truck Driver Date: @19/08/2026
Chief Complaints:
Syncope and Altered Level of Consciousness
Past Medical History:
Known Hypertensive
Presenting Illness:
47-year-old male, truck driver, presented with sudden syncope and ALOC. Initial ECG showed junctional bradycardia with 3rd degree AV block, HR 44, and ST changes in inferior leads. Trop I was markedly elevated at 50,000.
Cath study showed non-dominant RCA with 50% LAD lesion.
He was shifted to CCU-3 .
Course in CCU was complicated by severe hypoxemic respiratory failure. He required high ventilatory support: FiO2 70% PEEP 10 with initial P/F ratio 120. He underwent one session of prone positioning after which oxygenation improved. P/F ratio progressively improved: 120 → 100 → 180 → 190 → 220.
Hemodynamically he had evidence of impaired tissue oxygen delivery: initial ScvO2 54% with Pcv-aCO2 gap 12 mmHg. Milrinone was initiated with improvement in ScvO2 to 67%. Pcv-aCO2 gap remained ∼10 mmHg.
Key Investigations:
1. Labs:
• CBC: TLC 14.1
• RFTs: Cr 2.0
• LFTs: SGPT 1991, SGOT 1863, T.B 0.8
• Coags: INR 1.2
• Inflammatory markers: CRP 12.8, Procalcitonin 1.3
2. ABGs on ventilator:
• Initial: 7.31/36/84.1/18.1 on FiO2 70 PEEP 10
• Improved: 7.46/28/83/19 on FiO2 55 PEEP 10
• Latest: 7.48/28/86/20 on FiO2 40 PEEP 10
• VBG: 7.41/41/28.5/54
3. ECG: 3rd degree AV block, ventricular rate 44, non-specific lateral ST depression
4. Coronary Angiogram: Non-dominant RCA, non obstructive coronary
5. TTE 19/08/2026:
• LV: Normal size, normal systolic function. EF 55-60%. Atypical septal motion.
• RV: Dilated 45mm with depressed systolic function. TAPSE 11mm
• RA: Dilated 44mm
• Valves: Severe TR with poorly coapting leaflets. MV and AV structurally normal
• Impression: Dilated RV with depressed systolic function, Severe TR, Normal LV EF
6. CT Chest/Video:
Attached
Question:
What is the likely cause of hypoxemia in this patient??