Karshma Abbasi

01/02/2026

Groundbreaking medical research led by Dr. Mariano Barbacid at Spain’s National Cancer Research Centre (CNIO) has successfully achieved the complete and permanent elimination of pancreatic tumors in mouse models.

The study, published in January 2026 in the journal PNAS, utilized a innovative triple-drug combination therapy designed to bypass the tumor's typical resistance mechanisms.

This "triad" approach targets the KRAS oncogene pathway from three distinct angles: directly inhibiting the mutated KRAS protein, shutting down escape routes like the EGFR and HER2 pathways, and disabling the STAT3 stress-response system.

In experimental settings, this therapy led to full tumor regression with no recurrence for over 200 days post-treatment and notably low toxicity.

While these results mark a monumental step in oncology research, experts caution that the therapy has not yet entered human clinical trials and requires further validation for safety and efficacy in patients.

The breakthrough offers a new blueprint for treating pancreatic ductal adenocarcinoma, one of the world's most lethal and treatment-resistant cancers.

21/12/2025

انٽر پاس شاگرد هن مان ضرور فائدو حاصل ڪن
سنڌ ٽيلينٽ هنٽ پروگرام (STHP) تحت آءِ بي اي سکر طرفان هر سال جيان هن سال به غريب شاگردن لاءِ مفت اسڪالرشپ جو اعلان
سنڌ جا غريب شاگرد جيڪي يونيورسٽي جي پڙهائي جو خرچ ڀري نٿا سگهن تنهن لاءِ هي هڪ بهترين موقعو آهي، ان سان گڏوگڏ وظيفو هر مهيني ڏنو ويندو.
انٽر پاس شاگرد اهل هوندا ، ياد رهي ته اهڙا اميدوار جن 2023 ,2024 ,۽ 2025 ۾ انٽر پاس ڪيو هجي اهي اپلاءِ ڪري سگهن ٿا
آنلائن اپلاء ڪرڻ جي آخري تاريخ 09 جنوري 2026 آهي
داخلا لاء ٽيسٽ 18 جنوري 2026 تي ورتي ويندي .

31/10/2025

31/10/2025

HIV/AIDS SHOCK

OVER the past two decades, Pakistan has faced several HIV eruptions and the ignominy of ranking second among nations with the sharpest rise in HIV cases in the Asia-Pacific region.

Sadly, not even the scale of the crisis has spurred the government into action.

The Sindh health minister has been told about the “extremely alarming” HIV spread, which includes 3,995 registered HIV positive children in the province and over 600,000 fake doctors; 40pc operate in Karachi.

Officials cited unethical medical practices, risky blood transfusions from unregulated blood banks, contaminated syringes, dental equipment and razors, and the sale of hospital waste as causes.

The tragedy is compounded by violations of global SOPs. Mundane directives are not the way forward.

The calamity should compel the authorities to create accountability processes and databanks, with certified medics and ample resources to repair the rickety healthcare system.

The battle against HIV/AIDS involves a preventable and treatable virus; but the social stigma arising out of misconceptions has worsened matters.

Therefore, awareness about the causes and the manner in which the virus attacks the immune system should be created in schools and colleges.

Ending HIV/AIDS entails
reaching each patient and everyone at risk,

among them drug addicts, commercial s*x workers and the transgender community.

The authorities must scale up testing, crack down on quacks, ensure a steady supply of the mandatory antiretroviral therapy and implement stringent infection control measures at health units and blood banks.

Without a pro-citizen stance and global medical advancements to combat this health emergency, upsurges and mortalities cannot be blocked.

Additionally, policies and campaigns must be framed to alleviate poverty, keep children in school and create a reliable health infrastructure. Above all, societal attitudes have to change so that seeking treatment does not become a casualty of shame.

26/10/2025

MDCAT 2025

25/10/2025

Each of you has worked tirelessly for this day.

Remember, success favors the consistent and the brave.

Stay calm, stay positive, and let your brilliance show in every answer.
Best of luck, future doctors!"

01/10/2025

Japanese scientists have reported a landmark lab result: they successfully eliminated the extra chromosome 21 - the genetic cause of Down syndrome from cultured human cells.

The work, done in vitro using CRISPR technology, removed the third copy of chromosome 21 in a subset of trisomy-21 cells. This is an important step toward potential new therapies, but it has not been tested in humans and is far from a clinical cure.

Beyond the science, the achievement raises urgent ethical questions: should we set limits on genetic engineering? What does this mean for human diversity? Experts stress the need for caution, strict oversight, and broad public discussion before moving forward.

*Source: Mie University press release*

27/08/2025

Situation of students 😂

25/08/2025

2nd class of Carbohydrates

15/08/2025

Blood cells