Fhezt Bioinformatics

Fhezt Bioinformatics Applied Bioinformatics | Research & Training | Consultancy.

>>Introducing GABRIEL: Graduate Applied Bioinformatics Research Innovations and Experiential Learning
02/10/2025

>>Introducing GABRIEL: Graduate Applied Bioinformatics Research Innovations and Experiential Learning

>>Introducing GABRIEL: Graduate Applied Bioinformatics Research Innovations and Experiential Learning

Toluwase H. Fatoki In my previous paper, titled "Biomarketing: Understanding Brand Perception through Biological Proces...
03/03/2025

Toluwase H. Fatoki In my previous paper, titled "Biomarketing: Understanding Brand Perception through Biological Process, and User-Friendly Materials and Platforms". I wrote that "Clarity in health communication aids customer understanding of brand information." According to Blue Ocean Strategy, it is good to use "monitor meat freshness" instead of "detecting meat spoilage". This is what I termed "Bioactive Marketing" - a new positive language marketing strategy in the field of Biomarketing....

Toluwase H. Fatoki In my previous paper, titled "Biomarketing: Understanding Brand Perception through Biological Process, and User-Friendly Materials and Platfo…

Indigenous knowledge is the bedrock of cultural identity, societal advancement, and sustainable development. Nigeria, wi...
02/01/2025

Indigenous knowledge is the bedrock of cultural identity, societal advancement, and sustainable development. Nigeria, with its rich tapestry of traditions, languages, and innovations, holds an immense reservoir of indigenous wisdom that remains underutilized. These journals represent a powerful medium to document, share, and expand Nigeria's wealth of knowledge across various disciplines, from traditional medicine and agriculture to art, science, and technology....

Indigenous knowledge is the bedrock of cultural identity, societal advancement, and sustainable development. Nigeria, with its rich tapestry of traditions, languages, and innovations, holds an imme…

Amyotrophic lateral sclerosis (ALS) is a fatal, currently incurable neurodegenerative disease that progressively affects...
21/08/2024

Amyotrophic lateral sclerosis (ALS) is a fatal, currently incurable neurodegenerative disease that progressively affects the upper motor neurons in the brain and lower motor neurons in the spinal cord. A significant portion of patients exhibit abnormalities in lipid metabolism, which appear to contribute to denervation and subsequent motor neuron degeneration. This study aimed to computationally identify lipid-based compounds associated with ALS and elucidate their pathological and therapeutic roles to facilitate effective ALS diagnosis and treatment....

Amyotrophic lateral sclerosis (ALS) is a fatal, currently incurable neurodegenerative disease that progressively affects the upper motor neurons in the brain and lower motor neurons in the spinal c…

Superoxide dismutase 1 (SOD1), a copper-dependent enzyme, facilitates the conversion of superoxide anions into hydrogen ...
21/08/2024

Superoxide dismutase 1 (SOD1), a copper-dependent enzyme, facilitates the conversion of superoxide anions into hydrogen peroxide and oxygen, thereby regulating superoxide levels. Dysfunctions in SOD1 have been linked to neurodegenerative disorders such as amyotrophic lateral sclerosis, as well as liver and lung cancers. This study aimed to identify SOD1 modulators using in silico rational virtual enrichment screening, pharmacokinetics, docking, and molecular dynamic simulation (MDS)....

Superoxide dismutase 1 (SOD1), a copper-dependent enzyme, facilitates the conversion of superoxide anions into hydrogen peroxide and oxygen, thereby regulating superoxide levels. Dysfunctions in SO…

Cymbopogon citratus (DC) Stapf., is utilized in both culinary and medicinal contexts, wherein its extracts demonstrate a...
21/08/2024

Cymbopogon citratus (DC) Stapf., is utilized in both culinary and medicinal contexts, wherein its extracts demonstrate a range of therapeutic properties, including antidiabetic, antioxidant, and anti-inflammatory activities. This investigation aimed to computationally analyze phytochemicals of C. citratus, evaluating their pharmacokinetics and binding dynamics. The findings revealed a combination of high and low gastrointestinal absorption (GIA) for C. citratus (DC.) phytochemicals, with some exhibiting permeability across the blood-brain barrier (BBB)....

Cymbopogon citratus (DC) Stapf., is utilized in both culinary and medicinal contexts, wherein its extracts demonstrate a range of therapeutic properties, including antidiabetic, antioxidant, and an…

Introduction: The study investigated the molecular effects of human exposure to commonly used pesticides in Nigeria. Met...
21/08/2024

Introduction: The study investigated the molecular effects of human exposure to commonly used pesticides in Nigeria. Methods: Utilizing computational methods like clustering analysis, toxicokinetic predictions, molecular docking, and molecular dynamic (MD) simulation, various health impacts were identified. Results and Discussion: The results revealed significant gastrointestinal absorption, P-glycoprotein bypass, blood-brain barrier pe*******on, and cytochrome P450 inhibition for certain pesticide agents....

Introduction: The study investigated the molecular effects of human exposure to commonly used pesticides in Nigeria. Methods: Utilizing computational methods like clustering analysis, toxicokinetic…

Prostate cancer (PCa) is a complex and biologically diverse disease with no curative treatment options at present. This ...
05/07/2024

Prostate cancer (PCa) is a complex and biologically diverse disease with no curative treatment options at present. This study aims to utilize computational methods to explore potential anti-PCa compounds based on differentially expressed genes (DEGs), with the goal of identifying novel therapeutic indications or repurposing existing drugs. The methods employed in this study include DEGs-to-drug prediction, pharmacokinetics prediction, target prediction, network analysis, and molecular docking....

Prostate cancer (PCa) is a complex and biologically diverse disease with no curative treatment options at present. This study aims to utilize computational methods to explore potential anti-PCa com…

Introduction Exposure to rotenone could directly affects the function of mitochondrial which leads to neurodegeneration....
16/05/2024

Introduction Exposure to rotenone could directly affects the function of mitochondrial which leads to neurodegeneration. This study evaluated the therapeutic potential of taxifolin (Huāqí sōng dài; 花旗松甙) to alleviate metabolic and neurochemical alterations in the hippocampal and cortical region of brain of rotenone-toxified rats. Methods Male Wistar rats were subcutaneously administered 1.5 mg/kg rotenone for 10 days, followed by post-treatment with varying doses of taxifolin (0.25, 0.5 and 1.0 mg/kg) for 3 days through the same route....

Introduction Exposure to rotenone could directly affects the function of mitochondrial which leads to neurodegeneration. This study evaluated the therapeutic potential of taxifolin (Huāqí sōng dài;…

Welcome to Heze-Sapience International, where we're exploring the integration of Generative Artificial Intelligence (AI)...
05/04/2024

Welcome to Heze-Sapience International, where we're exploring the integration of Generative Artificial Intelligence (AI) in drug discovery. We're on a mission to transform healthcare by accelerating the development of novel therapeutics and improving patient outcomes. With our innovative approach, we invite you to join us in this exciting journey towards revolutionizing the pharmaceutical industry. Traditional drug discovery methods are time-consuming, costly, and often inefficient....

Welcome to Heze-Sapience International, where we’re exploring the integration of Generative Artificial Intelligence (AI) in drug discovery. We’re on a mission to transform healthcare by…

Annona muricata Lin is known for its ethnomedicinal uses as food, decoctions, or infusions to address various conditions...
05/04/2024

Annona muricata Lin is known for its ethnomedicinal uses as food, decoctions, or infusions to address various conditions like skin infections, fever, diabetes, insomnia, malaria, hypertension, nervous disorders, diarrhea, and cancer. The study aimed to analyze the phytochemicals such as acetogenins, alkaloids, cyclopeptides, and flavonoids, present in A. muricata fruit, evaluate their pharmacokinetics, and understand binding dynamics with key molecular targets relevant to human well-being....

Annona muricata Lin is known for its ethnomedicinal uses as food, decoctions, or infusions to address various conditions like skin infections, fever, diabetes, insomnia, malaria, hypertension, nerv…

❓How to learn bioinformatics 👨🏻‍💻Bioinformatics Computing 🎞Fall 2021 Recorded lectures + Slides from Edwards Lab in Geor...
14/03/2024

❓How to learn bioinformatics 👨🏻‍💻Bioinformatics Computing 🎞Fall 2021 Recorded lectures + Slides from Edwards Lab in Georgetown University. 💥This course provides a hands-on introduction to programming for bioinformatics using the scripting language Python. 📽 Introductory Clinical Bioinformatics 👩‍🏫 Bioinformatics course 2023 materials 💥University of California San Diego 👨‍🎓Free self-taught 4 year Curriculum of Bioinformatics!...

❓How to learn bioinformatics 👨🏻‍💻Bioinformatics Computing 🎞Fall 2021 Recorded lectures + Slides from Edwards Lab in Georgetown University. 💥This course provides a hands-on introduction to programmi…

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