Antimicrobial Resistance - AMR Awareness

ONE HEALTH
Summary: The vision that everything is connected in this world is not new. However, to respond to the current challenges that the world is facing, the integrated vision that humans, animals, and the environment are linked is more important than ever. Collaboration among multiple disciplines is crucial, and this approach is fundamental to understanding the One Health concept.

A transdisciplinary definition of One Health views animals, humans, and their shared settings or environment as linked and affected by the socioeconomic interest of humans and external pressures. A One Health concept calls for various disciplines to work together to provide new methods and tools for research and implementation of effective services to support the formulation of norms, regulations, and policies to the benefit of humanity, animals, and the environment for current and future generations. This will improve the understanding of health and disease processes as well as prediction, detection, prevention, and control of infectious hazards and other issues affecting health and well-being in the human-animal-ecosystem interface, contributing to sustainable development goals, and to improving equity in the world.
Keywordsanimal-human-ecosystem interfacemultidisciplinarytransdisciplinaryhuman health and agricultureintegrated vision

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“Its sceintifically proved that milk lactoferrin inhibits the growth of some pathogenic strains in humans and/or animals such as Escherichia coli, Salmonella typhimurium, Shigella dysenteriae, Listeria monocytogenes, Streptococcus spp., Vibrio cholerae, Legionella pneumophila, Klebsiella pneumophila, Enterococcus spp., Staphylococcus spp., Bacillus stearothermophilus and Bacillus subtilis.” - Prof Taherah

Camel milk lactoferrin against bacterial infections Due to the fact that camel milk has the highest amount of lactoferrin compared to other species, so it can be a valuable source of lactoferrin that can reduce bacterial growth, prevent bacterial ad…

Dear stakeholders,

Many antibiotics no longer work on our poultry and other livestock due to infection with resistant bacteria. We are losing money and our lives are in danger due to Antimicrobial Resistant infection.

To make a sense of this situation, please join our team of experts lead by Dr James Baba Wagetti (Adamore Nig. Ltd) for a webinar on a way forward.

Date : Saturday, Dec 19, 2020.
Time : 09:00 AM.

Zoom Link:
https://us02web.zoom.us/j/88343837954?pwd=NVFFemx3SHk1OHZuREN2R21KeWhndz09

Meeting ID: 883 4383 7954
Passcode: 633546

Proudly supported by Fleming Fund Project l 🇬🇧 UKAID l Dept social care.

Prudent and efficient use of antimicrobials in pigs and poultry. FAO Animal Production and Health Manual No. 23. Rome. FAO.

Antimicrobials are widely used in both humans and livestock and have greatly contributed to better human and animal health. However, these benefits are being threatened by the global emergence of antimicrobial resistance (AMR). Because humans and animals often share the same bacteria and may be treated with the same types of antibacterial drugs, resistance to antibiotics is the most critical aspect of AMR for the livestock sector. One way to mitigate the emergence of AMR is to reduce the overall use of antibiotics by combining prudent and medically rational use with other disease preventive measures.

This manual will contribute to addressing the challenge of AMR by promoting the prevention of infections and the prudent use of antibiotics in the pig and poultry sectors, the livestock sectors that generally have the highest use of antibiotics. It should be regarded as a practical complement to national governance and regulatory measures.
The manual is intended to assist pharmacists, veterinarians, other animal health workers, farm owners and their staff in using antibiotics in a prudent and medically efficient way without loss in productivity. It is especially targeted to farmers with commercialized medium- or large-scale production, veterinarians and other animal health personnel in non-EU Eastern European and Balkan countries, the Caucasus, and Central Asia, who are dealing with pigs and poultry. However, in many cases the principles and practices described here are universally useful and may be applied elsewhere.

The manual is available at: http://www.fao.org/documents/card/en/c/ca6729en andhttp://www.fao.org/3/ca6729en/CA6729EN.pdf



Best regards,

Daniela Battaglia

On behalf of the FAO Antimicrobial Resistance Interdepartmental Working Group

www.fao.org

Carryover in feed and transfer from feed to food of unavoidable and unintended residues of approved veterinary drugs - Report of the Joint FAO/WHO expert meeting – 8–10 January 2019, FAO headquarters, Rome, Italy

Dear all,
Carryover of veterinary drugs in feed can occur during feed processing, handling, transportation, delivery or in feeding animals on-farm. The risk of unavoidable
and unintentional veterinary drug residues from feed carryover and/or transfer from feed to food of animal origin is unacceptable when it causes adverse health effects in target and/or non-target animals and/or humans consuming food originating from these
animals. If carryover is not properly managed, contaminated feed can directly harm species that are sensitive to the unintended veterinary drug they consume, and /or can result in residues in food of animal origin such as meat, milk and eggs that render them
unsafe for human consumption. Even if residues are not a safety hazard, they can pose regulatory and global trade issue as countries/markets may enforce a “zero” tolerance for residues when appropriate maximum residue limits have not been established.

Upon request of the Codex Committee on Residues of Veterinary Drugs in Foods (CCRVDF), FAO and WHO convened an Expert Meeting to review the causes of veterinary drug carryover in animal feed and the transfer from feed to food, as well as the known risks to human health and international
trade, and suggest appropriate risk management strategies.
The report shows the results of the expert discussions, conclusions and recommendations and is available at:
http://www.fao.org/documents/card/en/c/ca6296en
If you interested in receiving an hard copy, please use the form available at https://www.surveymonkey.com/r/Z37YXTL

Best regards,
Daniela Battaglia
FAO Antimicrobial Resistance Interdepartmental Working Group

www.bukarusman.mege

COMBATING ANTIMICROBIAL RESISTANCE IN NIGERIA: MERGING ALL HANDS, ASSETS, COMPETENCE AND STAKEHOLDERS

Friday, January 27, 2017
ABUJA, NIGERIA

The Nigeria Centre for Disease Control, recently brought together experts from various Ministries and Agencies, academia and the private sector to chart a path towards a National Action Plan to combat antimicrobial resistance in Nigeria.

The threat of a time when antibiotics will fail to serve their roles in combating infectious diseases is currently the biggest fear of the entire global health system. Currently, reports of infections not responding to treatment with antibiotics are stressing countries around the world. Global projections are that resistance will cost the entire world $100Tn by 2050 if nothing is done. It is currently deepening the burden of otherwise treatable diseases including malaria, tuberculosis, HIV/AIDS and childhood infections. As they contemplate resistance, many countries complain of an inability to provide appropriate access to antibiotics to those who are in dire need of them. These factors coupled with the need to understand the scope of the challenge of antimicrobial resistance, and how best to combat it in Nigeria as a country, formed the basis for the convergence of this multisectorial think tank on antimicrobial resistance.

The group met between 16th and 17th of January, 2017 to review Nigeria’s requirement to complete her National Action plan and enroll in the Global Antimicrobial Surveillance System (GLASS) of the World Health Organisation. Enrollment on GLASS allows for transparent governance of AMR in countries, as well global assessment of state of the global health system.

Key expert recommendations are for countries to ensure a “One Health” and multistakeholder approach in the planning and implementation of their national antimicrobial resistance action planning and strategy. For this reason, participants at the meeting ensured that considerations of Animal Health, the Environment and Human Health were properly factored into all deliberations.

Representatives of the Federal Ministry of Health, Federal Ministry of Agriculture and Rural Development, National Agency for Food and Drug Administration and Control (NAFDAC), Nigeria Institute of Pharmaceutical Research (NIPRD), Nigeria Institute of Medical Research, National Veterinary Research Institute and academia participated in the development of a framework for national situation analysis for AMR as well the development of an action plan on AMR for Nigeria.

Nigeria’s current commitment to controlling antimicrobial resistance began on the first day of assumption of office by President Muhammad Buhari when he shared this country’s commitment to the global goal of protecting citizens from disease threats. This commitment was strengthened through Nigeria’s participation in World Health Assembly 2015 and the United Nations General Assembly 2016 where Nigeria signed to play her part as a country in combatting AMR. During the last UNGA, Prof Isaac Adewole, Nigeria’s Minister of Health, warned against complacency that could follow the declaration’s adoption: “We must not only talk but act. The time is now to fully implement this document.”

In furtherance to this global charge, the Nigerian government immediately appointed the Nigeria Centre for Disease Control to take a lead on this initiative of coordinating all relevant national actors to ensure Nigeria fulfills this key milestone before the 70th World Health Assembly in May, 2017.

The burden of AMR is primarily due to misuse of antibiotics. The ultimate outcome of this national intervention is to help reduce the heavy burden from resistance by galvanizing Nigerians to use of antibiotics responsibly, to make a more precise assessment of the current situation and burden, and to drive a national capacity building and resource commitment to ensuring the threats of AMR is under check in Nigeria and beyond.

According to the Director of Planning, Research & Statistics of the NCDC, Dr. Joshua Obasanya, “We at the NCDC hold ourselves extremely accountable for this coordination effort, our work is to ensure all relevant actors participate in this. We want to make sure that the One Health approach is evident as we combat AMR is Nigeria. This is the only way

to ensure our solutions are really sustainable”.

One of the technical leads at the meeting, Prof. Iruka Okeke of the Faculty of Pharmacy of the University of Ibadan also added that, “given the enthusiasm experienced during these sessions, I am optimistic that we will meet the required timeline towards a national action plan and AMR surveillance. It is clear, however, that a lot of work needs to be done. I congratulate the Federal Ministry of Health and the NCDC for taking the bold and critical steps needed for a strong start”.

Nigeria Centre for Disease Control The Nigeria Centre for Disease Control, recently brought together experts from various Ministries and Agencies, academia and the private sector to chart a path towards a National Action Plan to combat antimicrobial resistance in Nigeria.

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The Tripartite - a joint effort by the Food and Agriculture Organization (FAO), the World Organisation for Animal Health (OIE) and the World Health Organization (WHO), launched the AMR Multi-Partner Trust Fund, which is being supported by an initial contribution of $5 million from the Government of the Netherlands.

The AMR Trust Fund* has a five-year scope, through 2024, and aims to scale up efforts to support countries to counter the immediate threat of AMR, arguably the most complex threat to global health.

Antimicrobial resistance refers to the natural ability of bacteria and other microbes to develop resistance to the medicines we use to treat them, and the process is accelerated by inappropriate or excessive use of pharmaceutical products designed to kill unwanted pathogens in humans, animals and crops. In particular, the overuse and misuse of antibiotics in human and animal health is fueling resistance.

The rise of AMR, poses a threat described as a "silent tsunami". Drug-resistant microorganisms now account for an estimated 700,000 deaths a year, a figure that could increase to 10 million deaths each year if no action is taken.

"Combating antibiotics resistance is fundamentally a behaviour change issue. I'm not talking about washing hands more often, but about ensuring antibiotics are prescribed less readily and that work methods are changed to reduce the chance of resistant bacteria spreading," said the Netherlands Medical Care and Sports Minister Bruno Bruins. "This topic is so important that it deserves to stay at the top of the international political agenda. Countries have made outstanding plans and it's time now to carry them out. The Multi-Partner Trust Fund that we're launching today will help us do this because the problem is too big for countries to tackle alone," he added.

"Unfortunately, borders don't stop bacteria. But by pooling our efforts and knowledge, we can help each other combat AMR," said Carola Schouten, the Netherlands Minister of Agriculture, Nature and Food Quality. "There's still scope for improving the way antibiotics are used in livestock production, too. This conference is an excellent opportunity to engage in dialogue and learn from each other," she added.

"We all have a role to play to protect the efficacy of antimicrobial agents and the AMR Trust Fund gives us the opportunity to support the efforts of the different sectors at national, regional and global levels," said the OIE Director General, Dr Monique Eloit. "AMR must be addressed in a One Health approach and supported by long-term commitments from all stakeholders. The OIE is committed to supporting the animal health sector in fulfilling its commitments to ensure that both animals and humans will continue to benefit from available and efficient antimicrobials to treat their diseases for the future.

"FAO is fully dedicated to help eliminate hunger, food insecurity and malnutrition and dedicated to produce safe food for a growing world population in a sustainable way, said FAO Deputy-Director General, Climate and Natural Resources Maria Helena Semedo. "Antimicrobials are necessary tools to ensure food security, but they need to be used in a responsible way. FAO considers the Multi Partner Trust Fund as a milestone in our Tripartite efforts to reduce AMR" she added.

"This new Trust Fund signals an important new commitment to combat antimicrobial resistance. AMR is a serious challenge to reaching universal health coverage and a threat to achievement of the Sustainable Development Goals," said Dr Zsuzsanna Jakab, Deputy Director-General, WHO.

More information at:

FAO - News Article: New Multi-Partner Trust Fund launched to combat Antimicrobial Resistance globally The Tripartite - a joint effort by the Food and Agriculture Organization (FAO), the World Organisation for Animal Health (OIE) and the World Health Organization (WHO), launched the AMR Multi-Partner Trust Fund, which is being supported by an initial contribution of $5 million from the Government of....

: - Public Alert No. 0040/2018.

Alert on Falsified Costrim, Metronidazole, Domiquine, Catrim, Cemtrim 480 and Citrim 480 Tablets Manufactured by Mr. Emeka Madu (aka. Cabara).

The National Agency for Food and Drug Administration and Control (NAFDAC) alerts members of the public on the illegal manufacturing, distribution and sale of falsified Costrim Tablets, Metronidazole Tablets, Domiquine Tablets, Catrim Tablets, Cemtrim 480 Tablets and Citrim 480 Tablets by Mr. Emeka Madu (aka Cabara). These products are falsely labelled with the names of different manufacturers and falsified NAFDAC Registration Numbers to deceive unsuspecting members of the public.

The illegal manufacturing by Mr. Emeka Madu took place in an uncompleted and dilapidated twin building in a very filthy environment at Ikotun, Lagos. The Inspector-General of Police Intelligence Rapid Team (IGP-IRT) discovered the illegal manufacturing following a tip from an informant. NAFDAC and the Police jointly visited the production site where samples were taken for testing and processing. The site or the drugs were not registered by NAFDAC.

The use of falsified Costrim tablets, Metronidazole tablets, Domiquine tablets, Catrim tablets, Cemtrim 480 tablets and Citrim 480 tablets may result in treatment failures, development of drug resistance or even death.

NAFDAC implores distributors, wholesalers, retailers, healthcare providers, program managers and other members of the public to be vigilant and report anybody in possession of any of these falsified medicines to the nearest NAFDAC office.

Consumers are advised to report adverse events related to the use of any of these products to the nearest NAFDAC office, NAFDAC PRASCOR (20543 TOLL FREE from all networks) or via [email protected]

NAFDAC….Safeguarding the health of the nation!!!

NAFDAC bans use of antibiotics in animal feed - Punch Newspapers Anna Okon The National Agency for Food and Drug Administration and Control has issued a ban against the use of antibiotics (growth promoter and mould inhibitor) in animal feed. It has instead, encouraged the use of probiotics, enzymes and other healthy approved methods to enhance the growth and heal...

Dear Sir/Madam,

In recent years, antibiotic resistance has taken center stage globally with many developed countries employing multifaceted/multidisciplinary approaches to tackle this increasing challenge. As custodians of antibiotics in animal health, veterinarians play a critical role in ensuring the appropriate use of antibiotics.

Working in partnership with Ahmadu Bello University, Zaria and the University of Surrey, the African Livestock Productivity and Health Advancement (ALPHA) initiative team in Nigeria have designed a short online questionnaire to collect information about knowledge, attitude and practices of veterinarians towards antibiotics use and antibiotic stewardship. The information gathered will improve our understanding on this subject and help identify areas that could be targeted to improve prudent antibiotics use in veterinary practice in Nigeria

We would greatly appreciate if you could complete this online survey by Monday December 10 2018. The survey will take at most 15 minutes of your time to complete. Participation in the survey is voluntary; you can withdraw at any time if you feel uncomfortable to participate any further. No individual personal identifying data (including names and contact information) will be collected for purposes of the study.

The responses will be used to generate a report which will be shared with local stakeholders (including Federal Ministry of Agriculture and Rural Development and Nigeria Center for Disease Control) and disseminated further to the public through a peer reviewed publication.

If you have any questions or concerns regarding this study, please contact the research leads whose contact details are provided below.

Sincerely Yours,

Dr Usman O. Adekanye,
Telephone: +2348068576712, Email:[email protected]

Dr Beatty Viv Maikai
Department of Public Health and Preventive Medicine, Ahmadu Bello University, Zaria, Nigeria
Telephone: +2348135437243, Email:[email protected]

Dr Abel Ekiri
vHive, School of Veterinary Medicine, University of Surrey
Telephone: +44 (0) 1483688779, Email: [email protected]

Your participation in this survey is valued. Before proceeding to complete the survey, please indicate below your consent to participate by checking the appropriate option

https://surreyfahs.eu.qualtrics.com/jfe/form/SV_aY6msfKlZDaxg8t