24/05/2020
Biomedics delsu 2010
KEEPING IN TOUCH WITH COURSE MATES
24/05/2020
VACANCY ANNOUNCEMENT
The Nigerian Institute of Science Laboratory Technology (NISLT), a Federal Government Agency under the Federal Ministry of Science and Technology with the core mandate of “Advancing the Science Laboratory Technology” is seeking to recruits competent professionals with vast experience in laboratory Equipment repairs and maintenance.
POSITION:
I. Assistant Chief Laboratory Scientist / Assistant Chief Laboratory Technologist (Conraiss 12)
II. Principal Laboratory Scientist / Principal Laboratory Technologist (Conraiss 11)
III. Laboratory Scientist I / Laboratory Technologist I (Conraiss 8)
IV. Laboratory Scientist II / Laboratory Technologist II (Conraiss 7)
Note: All remunerations are based on the consolidated research and Allied Institutes salary scale.
DUTIES AND RESPONSIBILITIES
Carry out routine maintenance of Laboratory Equipment
Troubleshooting of faulty equipment
Maintaining equipment inventory
Calibration of laboratory equipment
QUALIFICATIONS
B.Tech /B.sc HND in Science Laboratory Technology (Physics/Electronics Option) from a recognized institution.
B.Tech / B.Sc in Physics with PMTE Certificate
M.sc In relevant field would be an added advantage
REQUIREMENTS
Applicants MUST be a Registered Member (Associate/Fellow) of NISLT with Current Annual License.
Applicants for Position (i) Must Possess At least 12 years Post qualification Hands-on experience in Laboratory Equipment Repairs and Maintenance.
Applicants for Position (ii) Must Posses At least 9 years Post qualification Hands-on experience in Laboratory Equipment Repairs and Maintenance.
Applicants for Position (iii) Must Posses At least 3 years Post qualification Hands-on experience in Laboratory Equipment Repairs and Maintenance.
Applicants should posses a good knowledge of Computers and relevant computer applications.
METHOD OF APPLICATION
All Interested Applicants should forward their written applications and Curriculum Vitae (CV) to [email protected], stating clearly the position applied for. The applications should be addressed to;
The Acting Registrar / DG / CEO
NISLT, Ibadan
CLOSING DATE
Application closes @ 11:59pm, Friday, 9th September, 2016.
Please note that only short listed candidates would be contacted.
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Sequence analysis of mutations and translocations across breast cancer subtypes.
AuthorsBanerji S, et al. Show all Journal
Nature. 2012 Jun 20;486(7403):405-9. doi: 10.1038/nature11154.
Affiliation
The Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
Comment in
Nat Rev Cancer. 2012 Aug;12(8):507.
Nature. 2012 Jun 21;486(7403):328-9.
Abstract
Breast carcinoma is the leading cause of cancer-related mortality in women worldwide, with an estimated 1.38 million new cases and 458,000 deaths in 2008 alone. This malignancy represents a heterogeneous group of tumours with characteristic molecular features, prognosis and responses to available therapy. Recurrent somatic alterations in breast cancer have been described, including mutations and copy number alterations, notably ERBB2 amplifications, the first successful therapy target defined by a genomic aberration. Previous DNA sequencing studies of breast cancer genomes have revealed additional candidate mutations and gene rearrangements. Here we report the whole-exome sequences of DNA from 103 human breast cancers of diverse subtypes from patients in Mexico and Vietnam compared to matched-normal DNA, together with whole-genome sequences of 22 breast cancer/normal pairs. Beyond confirming recurrent somatic mutations in PIK3CA, TP53, AKT1, GATA3 and MAP3K1, we discovered recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1. Furthermore, we have identified a recurrent MAGI3-AKT3 fusion enriched in triple-negative breast cancer lacking oestrogen and progesterone receptors and ERBB2 expression. The MAGI3-AKT3 fusion leads to constitutive activation of AKT kinase, which is abolished by treatment with an ATP-competitive AKT small-molecule inhibitor.
PMID 22722202 [PubMed - indexed for MEDLINE]
Full text: Nature Publishing Group
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