Tilraunastöð Háskóla Íslands að Keldum

Laust starf - Forstöðumaður Tilraunastöðvar Háskóla Íslands í meinafræði að Keldum.

Forstöðumaður Tilraunastöðvar Háskóla Íslands í meinafræði að Keldum | Ísland.is Laust er til umsóknar fullt starf forstöðumanns Tilraunastöðvar Háskóla Íslands í meinafræði að Keldum (Keldur), sem jafnframt er prófessor við Læknadeild innan Heilbrigðisvísindasviðs Háskóla Íslands með takmarkaða kennsluskyldu samkvæmt nánari ákvörðun háskólaráðs. ...

Kolfinna Pola Frantzen Grétarsdóttir - Diplómaritgerð er komin á Skemmuna. Mat á sértækum ræktunaraðferðum fyrir Campylobacter spp. / Evaluation of selective culture methods for Campylobacter spp.

Human Verification Ljúktu við CAPTCHA hér að neðan til að fá aðgang að vefnum. Complete the CAPTCHA below to receive access to the website.

Yara Aparecida Evangelista - MS ritgerð er komin á Skemmuna. Escherichia coli stofnar tengdir slefsýki í nýfæddum lömbum / Escherichia coli associated with watery mouth disease in neonatal lambs:

Human Verification Ljúktu við CAPTCHA hér að neðan til að fá aðgang að vefnum. Complete the CAPTCHA below to receive access to the website.

Frábær umfjöllun um þau mikilvægu og fjölbreyttu verkefni sem Keldur sinna á sviði dýraheilbrigðis í þættinum Meðal fólks á Rás 1, kl. 13, í dag.

Dagskrá útvarps - Spilari RÚV Útvarp

New article in „Appl Environ Microbiol“ – „Villamil-Alonso A, Moldal T, Bøe CA, Bragason BT, Nilsen H, Olsen AB, Garseth ÅH, Gulla S, Vendramin N, Madsen L, Cuenca A, Lagesen K.0.Whole-genome sequencing reveals a novel Renibacterium salmoninarum lineage and suggests geographic endemism combined with anthropogenic spread in the North-East Atlantic Area. Appl Environ Microbiol 0:e00347-26, 2026“. ABSTRACT: Renibacterium salmoninarum is the causative agent of bacterial kidney disease (BKD) and has been isolated from northern European salmonid farms since the 1960s. The bacterium has been detected only sporadically in Norway during the last few decades, but the country has experienced several geographically spread outbreaks since December 2022. The phylogenomic relationships of R. salmoninarum isolates associated with the epizootics ongoing on the West Coast and in Mid-Norway were explored using draft genomes generated by whole-genome sequencing. A broad overview of the phylogeography of this pathogen was gained through sequencing and analysis of a collection of isolates from Norway (n = 67), Iceland (n = 12), Denmark (n = 12), and the Faroe Islands (n = 1), along with a collection of 109 publicly available sequences. We identified two distinct contemporary clades of R. salmoninarum causing BKD in Norway in the period 2022–2024. Both clades belong to the expanding, aquaculture-associated Lineage 1. The epidemiological picture appears consistent with contemporary aquaculture operations, raising questions on the effectiveness or practice of current biosecurity practices toward R. salmoninarum. This work also describes a hitherto undescribed lineage (Lineage 3), predominantly from Iceland, where BKD is considered endemic. The detection of endemic reservoirs of R. salmoninarum in European water systems underscores the potential for ongoing pathogen circulation independent of acute outbreaks. This finding emphasizes the importance of further investigation of the mechanisms of pathogen persistence, particularly within environments related to aquaculture, where chronic infection reservoirs could compromise disease management and biosecurity. IMPORTANCE: Renibacterium salmoninarum, the causative agent of bacterial kidney disease (BKD), is a salmonid pathogen that often presents as subclinical, chronic infections, complicating detection and control. Effective management of BKD is crucial for sustainable aquaculture and wild fish conservation. Recognizing the need for comprehensive sampling, previous studies have underscored the importance of a global isolate collection to better understand the pathogen’s epidemiology. While the slow genetic evolution and highly conserved genome of the bacterium have reduced the resolution of conventional typing methods in the past, applying whole-genome sequencing has enabled its molecular tracing at the outbreak level. Here, we present the largest phylogenomic analysis of R. salmoninarum to date, including sequences from Denmark, Iceland, and the Faroe Islands for the first time. This expanded data set elucidates past and present movements of the pathogen in European waters, providing actionable insights to support development of targeted BKD management and biosecurity strategies.

Whole-genome sequencing reveals a novel Renibacterium salmoninarum lineage and suggests geographic endemism combined with anthropogenic spread in the North-East Atlantic Area | Applied and Environmental Microbiology Renibacterium salmoninarum, the causative agent of bacterial kidney disease (BKD), is a salmonid pathogen that often presents as subclinical, chronic infections, complicating detection and control. Effective management of BKD is crucial for sustainable aquaculture and wild fish conservation. Recogni...

New article in „Journal of Helminthology“ – „Higueruelo A, Dallarés S, Schaeffner BC. Hidden in the dark: description of Calicotyle carmenae n. sp. (Monogenea: Monocotylidae) from deepwater catsharks (Elasmobranchii: Pentanchidae) off Iceland. Journal of Helminthology 100:e57, 2026". Abstract: A new species of Calicotyle (Monogenea: Monocotylidae) is described from three deepwater catshark species (Elasmobranchii: Pentanchidae) collected off Iceland. Calicotyle carmenae n. sp. is diagnosed as a species of Calicotyle possessing a haptor with one central and seven peripheral loculi, two hamuli, and several hooklets. It is distinguished from all congeners by the absence of eye spots, having a once-looped male copulatory organ, two U-shaped vaginae, and intercaecal vaginal pores. A molecular phylogenetic analysis based on 28S ribosomal DNA sequences placed Calicotyle carmenae n. sp. within a clade of other Calicotyle species infecting selachians and holocephalans, while revealing clear genetic divergence from these congeners (8.2–11.1%; 74–99 bp). In addition, the morphology and host specificity of C. carmenae and its congeners are discussed. Some inconsistencies and insufficiently described anatomical features in other species of the subfamily Calicotylinae are highlighted, which evidence a need for a revision of this taxon. The study also provides the first record of a species of Calicotyle from pentanchid sharks, highlighting the potential for further discoveries as research expands into different hosts and deeper, underexplored marine ecosystems.

Hidden in the dark: description of Calicotyle carmenae n. sp. (Monogenea: Monocotylidae) from deepwater catsharks (Elasmobranchii: Pentanchidae) off Iceland | Journal of Helminthology | Cambridge Core Hidden in the dark: description of Calicotyle carmenae n. sp. (Monogenea: Monocotylidae) from deepwater catsharks (Elasmobranchii: Pentanchidae) off Iceland - Volume 100

Meistaragráða veitt Thelmu Rakel Ottesen.

Meistaragráða veitt Thelmu Rakel Ottesen | Keldur

Diplómagráða veitt Kolfinnu Polu Frantzen Grétarsdóttur.

Diplómagráða veitt Kolfinnu Polu Frantzen Grétarsdóttur | Keldur Kolfinna Pola Frantzen Grétarsdóttir kynnti 15. maí diplómaverkefnið sitt í lífeindafræði, sem unnið var á Keldum. Ritgerðin ber heitið: Evaluation of selective culture methods for Campylobacter spp. Comparison of selective media, enrichment broths, and spike levels. Á íslensku: Mat ...

Thelma Rakel Ottesen ver MS ritgerð sína næsta miðvikudag 20. maí 2026. "Samanburður á ónæmisglæðum og bólusetningaraðferðum gegn sumarexemi í hestum. Comparison of adjuvants and vaccination methods for insect bite hypersensitivity in horses". Leiðbeinendur: Sigríður Jónsdóttir og Vilhjálmur Svansson. Þriðji maður í MS nefnd er Siggeir Fannar Brynjólfsson. Prófið fer fram í Læknagarði HÍ kl. 11:00. Prófari: Stefanía P. Bjarnarson.

Meistarapróf í Læknadeild Háskóli Íslands býður upp á fjölbreytt nám á grunn og framhaldsstigi. Lögð er áhersla á fræðilega nálgun og rannsóknatengt nám með góð tengsl við atvinnulíf og nýsköpun

New article in „Front Immunol“ – „Natale S, Savoca S, Capparucci F, Capillo G, Mancuso M, Bragason BT, Riolo K, Giannetto A, Marino F and Iaria C. Evaluation of Imoviral® effects on early immune response in Sparus aurata challenged with Vibrio anguillarum. Front Immunol 17:1681468, 2026“. Abstract: Background: An acute phase response (APR) was experimentally induced in Sparus aurata (Linnaeus, 1758) by intraperitoneal (IP) injection of Vibrio anguillarum to evaluate the effects of dietary supplementation with the Imoviral® complex (CRISTALFARMA) on fish growth performance and health status, through the analysis of key genes involved in the APR. Imoviral® is a blend of exclusively natural extracts, i.e. uncaria (Uncaria tomentosa), shiitake (Lentinula edodes), beta-glucan and black-currant (Ribes nigrum), whose immunostimulant and analgesic properties have already been demonstrated in humans. Methods: One hundred S. aurata specimens 12.96 ± 0.93 grams, obtained from a fish farm, were used and divided into 5 experimental groups (in duplicate). After the feeding period, an experimental IP infection with V. anguillarum was performed and the APR evaluated at different time points i.e., 1, 24, 72, and 168-hours post infection. The expression of key genes involved in immune and oxidative stress responses, including IL-1β, TNF-α, defensin, hepcidin, catalase, Copper-zinc superoxide dismutase and magnesium superoxide dismutase, Glutathione S-Transferase, TGF-β and Interleukin-10 was evaluated through RT-qPCR and compared to control groups. Results: The Imoviral® diet did not affect growth performance, as all groups showed 100% survival and no significant differences in morphometric parameters. Immune-gene modulation revealed that IVS fish exhibited early and transient upregulation of TNF-α and IL-1β, while PVS fish displayed a sustained and stronger pro-inflammatory response. Antimicrobial peptides (hepcidin, defensin) were markedly overexpressed only in PVS, whereas Imoviral® fed groups showed limited or temporally controlled changes. Oxidative-stress genes (CAT, CuZnSOD, MnSOD) were strongly induced in PVS, with IVS showing more moderated patterns. Cellular metabolism marker GST was significantly modulated across treatments, with IVS showing consistent differences, indicating a possibly more balanced oxidative and immune response under Imoviral® supplementation. Conclusion: The present findings support the hypothesis that Imoviral® may serve as a promising immunostimulant and/or antibacterial dietary supplement for farmed gilthead sea bream, providing a solid basis for future investigations in this area.

Frontiers | Evaluation of Imoviral® effects on early immune response in Sparus aurata challenged with Vibrio anguillarum BackgroundAn acute phase response (APR) was experimentally induced in Sparus aurata (Linnaeus, 1758) by intraperitoneal (IP) injection of Vibrio anguillarum ...