02/10/2026
Does tamoxifen cause bone loss? It depends entirely on your menopausal status, premenopausal, perimenopausal, or postmenopausal and that’s the part most warnings leave out.
In postmenopausal women, tamoxifen protects bone density.
In premenopausal women, tamoxifen is linked to measurable bone loss, mainly in the spine.
Perimenopausal women fall into a grey zone current guidelines don’t fully address.
⭐️ACS/ASCO bone density screening guidelines recommend a DEXA scan every 2 years for premenopausal women on tamoxifen, based on real bone loss seen in trials.
⭐️But real-world fracture data doesn’t fully agree, which is exactly why advice on tamoxifen and bone health can feel inconsistent.
⭐️Part 2 covers who needs a baseline bone scan and when the risk goes up. Follow Farah Dutson | Breast Cancer | Osteoporosis | Menopause so you don’t miss it.
Did anyone actually explain this to you, or did you find out by yourself? Tell me in the comments⬇️