DrugXperts.com

Do you believe in corticosteroids all the time?

Then, Check this out
Effect of oral prednisolone on symptom duration in lower respiratory tract infection

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http://jamanetwork.com/journals/jama/article-abstract/2649201?utm_source=FBPAGE&utm_medium=social_jn&utm_term=1034310926&utm_content=content_engagement%7carticle_engagement&utm_campaign=article_alert&linkId=41373876

Effects of Oral Prednisolone on Symptom Duration in Lower Respiratory Tract Infection This randomized trial compares the effect of prednisolone vs placebo on duration of moderately bad or worse cough and severity of symptoms in nonasthmatic adults with acute lower respiratory infections.

AACE 2017 Guidelines

GUIDELINES FOR MANAGEMENT OF DYSLIPIDEMIA AND PREVENTION
OF CARDIOVASCULAR DISEASE
Link for download :https://www.aace.com/files/lipid-guidelines.pdf

www.aace.com

Deprescribing proton pump inhibitors:

Proton pump inhibitors are often viewed as safe and well tolerated medications, and while the incidence of side effects, such as diarrhea,impaired B12 absorption, hypomagnesemia, Clostridium difficile infection, hip fractures, and pneumonia might be small, older people might be at higher risk of these conditions. When PPIs are inappropriately prescribed or used for too long, they can contribute to polypharmacy with its attendant risks of nonadherence, prescribing cascades, adverse reactions, medication errors, drug interactions, emergency department visits, and hospitalization
The target population includes adults older than 18 years of age (including the elderly) taking a continuous PPI for longer than 28 days for the purpose of treating GERD or esophagitis. The guideline does not apply to those with Barrett esophagus, those with severe esophagitis ,or those with documented history of bleeding gastrointestinal (GI) ulcers. Individual situations in which there might be risk factors that warrant continued use of PPIs are also outlined.



Reference :
http://www.cfp.ca/content/63/5/354.long

Thiazide diuretics can contribute to each of the following
metabolic effects EXCEPT
A. Hypomagnesemia
B. Hypouricemia
C. Hypercalcemia
D. Hypertriglyceridemia
E. Hyponatremia

Ticagrelor versus Clopidogrel in symptomatic PAD patients

Ticagrelor did not demonstrate a benefit over clopidogrel in symptomatic peripheral artery disease (PAD) patients, according to the results of the EUCLID Trial -
See more at: https://www.acc.org/latest-in-cardiology/articles/2016/11/10/15/11/sun-445pmet-euclid-effects-of-ticagrelor-vs-clopidogrel-in-pad-aha-2016 .o3CDSkKJ.dpuf
https://www.acc.org/latest-in-cardiology/articles/2016/11/10/15/11/sun-445pmet-euclid-effects-of-ticagrelor-vs-clopidogrel-in-pad-aha-2016

EUCLID: Ticagrelor vs. Clopidogrel in Symptomatic PAD Patients - American College of Cardiology Ticagrelor did not demonstrate a benefit over clopidogrel in symptomatic peripheral artery disease (PAD) patients, according to the results of the

2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis

https://academic.oup.com/cid/article/2996079/2017-Infectious-Diseases-Society-of-America-s?searchresult=1

2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis* | Clinical Infectious Diseases | Oxford Academic Allan R. Tunkel, Rodrigo Hasbun, Adarsh Bhimraj, Karin Byers, Sheldon L. Kaplan, W. Michael Scheld, Diederik van de Beek, Thomas P. Bleck, Hugh J.L. Garton, Joseph R. Zunt; 2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningit...

Which of the following statements about diuretics in heart
failure is true?
A. Mannitol is an effective diuretic in cardiac surgical
patients with decompensated heart failure
B. Aldosterone receptor antagonists lessen the tendency of
ACE inhibitors to cause hyperkalemia
C. Loop diuretics often result in hypokalemia and metabolic
acidosis
D. The effectiveness of loop diuretic agents is reduced by
nonsteroidal anti-inflammatory drugs

Cost-Effectiveness of Histamine2 Receptor Antagonists Versus Proton Pump Inhibitors for Stress Ulcer Prophylaxis in Critically Ill Patients

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Cost‐Effectiveness of Histamine2 Receptor Antagonists Versus Proton Pump Inhibitors for Stress Ulcer Prophylaxis in Critically Ill Patients To determine the cost‐effectiveness of stress ulcer prophylaxis with histamine2 receptor antagonists (H2RAs) versus proton pump inhibitors (PPIs) in critically ill and mechanically ventilated adults.A...

The holidays don’t just bring joy, they also bring an increase in heart attacks. Know the warning signs of a heart attack before it’s too late. Act now to learn more. http://spr.ly/61858zsMN
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The holidays don’t just bring joy, they also bring an increase in heart attacks. Know the warning signs of a heart attack before it’s too late. Act now to learn more. http://spr.ly/61858zsMN