13/10/2026
SOVS Paper of the Week: This study explores combining conventional antibiotics with membrane-active peptides to enhance activity against WHO-priority multidrug- and extensively drug-resistant Gram-negative ocular pathogens and identify promising strategies to combat antimicrobial resistance.
Background/objectives: Multidrug-resistant and extensively drug-resistant Gram-negative pathogens are a major cause of severe ocular infections, yet treatment options are increasingly compromised by escalating antibiotic resistance. Membrane-active peptides (colistin and Mel4) offer the potential to...