LSU Health Shreveport School of Graduate Studies

Graduate Studies Program offering M.S., Ph.D., & M.D./Ph.D. degrees in the Departments of:
Biochemistry & Molecular Biology
Cellular Biology & Anatomy
Microbiology & Immunology
Molecular & Cellular Physiology
Pharmacology, Toxicology & Neuroscience

The official page for LSU Health Sciences Center, Shreveport, School of Graduate Studies information.

Operating as usual

09/17/2021

Shashanka's favorite courses in graduate school have been cell biology and biochemistry. But his favorite technique lately is an interesting one used to understand bioenergetics of the cell by measuring mitochondrial function through the Seahorse assay, which measures oxygen consumption rate. Shank also enjoys mass spectrometry for its sensitivity and precision, which allows him to detect and understand biomolecules at the atomic level.

Shashanka's favorite courses in graduate school have been cell biology and biochemistry. But his favorite technique lately is an interesting one used to understand bioenergetics of the cell by measuring mitochondrial function through the Seahorse assay, which measures oxygen consumption rate. Shank also enjoys mass spectrometry for its sensitivity and precision, which allows him to detect and understand biomolecules at the atomic level.

09/15/2021

At a recent annual meeting of the American Heart Association in Philadelphia, PA, Shashanka Rao was able to present his research. His poster was titled, "Nicotinamide Nucleotide Transhydrogenase (NNT) regulates mitochondrial function and oxLDL Induced Macrophage/Endothelial Interaction".

At a recent annual meeting of the American Heart Association in Philadelphia, PA, Shashanka Rao was able to present his research. His poster was titled, "Nicotinamide Nucleotide Transhydrogenase (NNT) regulates mitochondrial function and oxLDL Induced Macrophage/Endothelial Interaction".

09/14/2021

At 4pm in 5-201, Ashton Jorgensen, a student in the Department of Pharmacology, Toxicology and Neuroscience, will be presenting a seminar based on her research, titled, "The Role of Neurogranin During Endothelial Activation."

At 4pm in 5-201, Ashton Jorgensen, a student in the Department of Pharmacology, Toxicology and Neuroscience, will be presenting a seminar based on her research, titled, "The Role of Neurogranin During Endothelial Activation."

09/14/2021

Today at 4pm in 5-201, Julie Tobin, a student in the Department of Pharmacology, Toxicology, & Neuroscience, will present a seminar based on her research, titled, "Metabolism of Diglycolic Acid".

Today at 4pm in 5-201, Julie Tobin, a student in the Department of Pharmacology, Toxicology, & Neuroscience, will present a seminar based on her research, titled, "Metabolism of Diglycolic Acid".

09/13/2021

As a student in the Department of Cellular Biology and Anatomy, Shashanka Rao teaches anatomy to students within the School of Allied Health Professions. He was voted the Best Student Teacher by the students he teaches.

As a student in the Department of Cellular Biology and Anatomy, Shashanka Rao teaches anatomy to students within the School of Allied Health Professions. He was voted the Best Student Teacher by the students he teaches.

Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II 09/10/2021

Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II

Our Graduate Student of the Month, Shashanka, recently published an impressive paper in Redox Biology.
Check out the paper by following the link below: https://www.sciencedirect.com/science/article/pii/S2213231720308557

Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II Endothelial dysfunction is a critical, initiating step in the development of hypertension (HTN) and mitochondrial reactive oxygen species (ROS) are im…

09/10/2021

Fall 2022 Applications

Fall 2022 Applications are now open!

To apply, visit our website:
https://lsuhs.edu/our-schools/school-of-graduate-studies/admissions
or GradCAS: https://gradcas2022.liaisoncas.com/applicant-ux/#/deeplink/programSearch/organization/389103855081155771

[09/08/21]   The title of Shashanka Rao's dissertation is "The effect of mitochondrial antioxidant enzyme Nicotinamide nucleotide transhydrogenase (NNT) on cardiovascular diseases". This is how he describes his project:
"Mitochondria generates toxic reactive oxygen species (ROS) during the process of energy generation, and NNT is present upstream of mitochondrial antioxidant enzymes which neutralizes toxic ROS to water. In cardiovascular pathology such as atherosclerosis and hypertension, NNT functions sub power leading to progression of disease outcomes. We are trying to understand the regulation of this enzyme both in-vitro and in-vivo to improve cardiovascular outcomes."

[09/06/21]   Shashanka Rao is from Bangalore, India. He obtained his previous degree in 2010 from Sir MVIT in his hometown in engineering in biotechnology and molecular biophysics. Before coming to to graduate school at LSU Health Shreveport, he had research experience in analyzing the metal ion-dependent aggregation of amyloid Aβ plaques in Alzheimer’s disease.

09/03/2021

The September Graduate Student of the Month is Shashanka Rao KM! Shashanka "Shank" Rao joined the Department of Cellular Biology and Anatomy in the fall of 2016. He currently works in the lab of Dr. David Krzywanski. Stay tuned to learn more about Shank all month!
#LSUHS #LSUHSgradstudies #LSUHSGradstudentofthemonth

The September Graduate Student of the Month is Shashanka Rao KM! Shashanka "Shank" Rao joined the Department of Cellular Biology and Anatomy in the fall of 2016. He currently works in the lab of Dr. David Krzywanski. Stay tuned to learn more about Shank all month!
#LSUHS #LSUHSgradstudies #LSUHSGradstudentofthemonth

Graduate Studies Welcome Day 09/03/2021

Graduate Studies Welcome Day

Here is a video from our Fall Welcome Day event!

https://www.youtube.com/watch?v=HTPQ8yptlRM

Graduate Studies Welcome Day The School of Graduate Studies at LSU Health Shreveport recently held its annual Welcome Day for new students. One upperclassman from each department gave a ...

Graduate Studies Welcome Day 09/03/2021

Graduate Studies Welcome Day

The Graduate Student Council recently organized the annual Fall Welcome which allows new graduate students an opportunity to become acquainted with their peers and learn about the research they are conducting. LSUHS Alumna and guest speaker, Delira Robbins, PhD, discussed her career path from graduate school to her current position at St. Jude Children’s Research Hospital.

Graduate Studies Welcome Day The School of Graduate Studies at LSU Health Shreveport recently held its annual Welcome Day for new students. One upperclassman from each department gave a ...

Photos from LSU Health Shreveport School of Graduate Studies's post 08/31/2021

Today is our last day to showcase the August Graduate Student of the Month, Siyuan Cheng.
Siyuan wants potential and junior graduate students to know that you shouldn't get frustrated with negative data in your research. It is normal to have lots of negative results, but it's important not to give up!

08/30/2021

Siyuan Cheng says that one of the reasons he chose LSU Health Shreveport was because he liked the lab rotation policy and thought it would give him a wide variety of skills and experiences. Since becoming a student, he has grown to love Shreveport in general, and the institution's research environment.

Siyuan Cheng says that one of the reasons he chose LSU Health Shreveport was because he liked the lab rotation policy and thought it would give him a wide variety of skills and experiences. Since becoming a student, he has grown to love Shreveport in general, and the institution's research environment.

Local pediatric doctor answers parent’s questions about COVID-19 08/30/2021

Local pediatric doctor answers parent’s questions about COVID-19

Local pediatric doctor answers parent’s questions about COVID-19 (KTAL/KMSS) – Now that kids are back in school and more COVID-19 cases are being reported among young people, parents have many questions about what to watch for and how to protect their children. …

08/28/2021

Siyuan Cheng says he came to graduate school because he wanted to be the first person in the world to get answers to previously unanswered questions. Don't you think that one of the coolest ways to look at being a graduate student?!

Siyuan Cheng says he came to graduate school because he wanted to be the first person in the world to get answers to previously unanswered questions. Don't you think that one of the coolest ways to look at being a graduate student?!

Photos from LSU Health Shreveport's post 08/28/2021

Another successful Fall Welcome Day!

08/28/2021
08/27/2021

After graduate school, Siyuan plans to begin a post-doctoral fellowship or start a career as a data scientist.

After graduate school, Siyuan plans to begin a post-doctoral fellowship or start a career as a data scientist.

08/27/2021

Today is the big day--don't miss out on Fall Welcome Day LSU Health Shreveport School of Graduate Studies hosted by the Graduate Student Council!

Today is the big day--don't miss out on Fall Welcome Day LSU Health Shreveport School of Graduate Studies hosted by the Graduate Student Council!

Photos from Department of Molecular & Cellular Physiology's post 08/25/2021

Photos from Department of Molecular & Cellular Physiology's post

[08/25/21]   Sharing your data before it's published is an important part of the scientific process. When Siyuan gets new data, he likes to share it with his mentor, Dr. Xiuping Yu, of the Dept. of Biochemistry & Molecular Biology, LSUHSC- S.

Photos from LSU Health Shreveport's post 08/25/2021

We were so happy to host Governor Edwards today.
And you read that correctly—the School of Graduate Studies is 100% vaccinated!

08/23/2021

In his spare time, Siyuan Cheng enjoys staying active by playing basketball. He also enjoys working on his bright yellow car. He's always easy to spot around town!

In his spare time, Siyuan Cheng enjoys staying active by playing basketball. He also enjoys working on his bright yellow car. He's always easy to spot around town!

08/23/2021

Graduate Students: Don't forget about Fall Welcome Day on Friday! We can't wait to see you there!

Graduate Students: Don't forget about Fall Welcome Day on Friday! We can't wait to see you there!

Photos from LSU Health Shreveport School of Graduate Studies's post 08/19/2021

Check out our students in their lab coats from their most recent event! We even included some bloopers for you.
Even Drs. Kevil and Tatchell got in on the fun!

08/19/2021

Siyuan Cheng's favorite course in graduate school was genetics, which factors heavily into his research. His favorite techniques are RT-qPCR and RNA-seq. For all of our non-basic science followers, here's a quick rundown of RT-qPCR courtesy of ThermoFisher Scientific:

Siyuan Cheng's favorite course in graduate school was genetics, which factors heavily into his research. His favorite techniques are RT-qPCR and RNA-seq. For all of our non-basic science followers, here's a quick rundown of RT-qPCR courtesy of ThermoFisher Scientific:

[08/17/21]   Our Graduate Student of the Month, Siyuan, recently received the Carroll Feist Pre-Doctoral Fellowship. His application was based on his dissertation work in prostate cancer.

08/17/2021

As part of Wellness Week at LSU Health Shreveport, Candy Galore and More will be here from 11:30am to 1:30pm. Be sure to stop by!

As part of Wellness Week at LSU Health Shreveport, Candy Galore and More will be here from 11:30am to 1:30pm. Be sure to stop by!

Photos from LSU Health Shreveport's post 08/16/2021

Photos from LSU Health Shreveport's post

08/13/2021

Siyuan Cheng has presented his research at the conference of the American Association of Cancer Research twice. The first was in 2019, titled, "AR signaling promotes prostate carcinogenesis". His second was in 2020, titled, "2. Loss of YAP1 activates Wnt/beta-Catenin signaling in prostate cancer".

Siyuan Cheng has presented his research at the conference of the American Association of Cancer Research twice. The first was in 2019, titled, "AR signaling promotes prostate carcinogenesis". His second was in 2020, titled, "2. Loss of YAP1 activates Wnt/beta-Catenin signaling in prostate cancer".

The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer - Prostate Cancer and Prostatic Diseases 08/11/2021

The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer - Prostate Cancer and Prostatic Diseases

In his last few years here at LSU Health Shreveport, Siyuan was able to publish his work multiple times. Check out the links to learn more!
https://www.nature.com/articles/s41391-020-0229-z.epdf?sharing_token=hanT-S0_YrCfLYiNRPpAP9RgN0jAjWel9jnR3ZoTv0PmXm5PO4h6JsV0lPpYPLlRlr6j2uEprlwbBmRA6SNSbGq1sM-JHfcybjVoVyvzOtPsMcrtfEOcW8GFa8unFgzhkI-dKmqYuKlltiB2ubu0mV3NKBnRdrMi7soIxQc_VXM%3D
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872473/
https://www.nature.com/articles/s41598-021-82472-1.epdf?sharing_token=m1NdMMESjBmNHHKjkwEN3tRgN0jAjWel9jnR3ZoTv0MDm4bQW8TBXm8B69TclOFS4xFzNdvZSjmGqowno7TvNYS9M-cfG1dkGwEcEBT0R3HPD8g51Pac0HiD3BlOuCAvbfXs5wFcu12nAEIxqKBjYysieDxY_O6_T8VtLl20b4s%3D
https://www.nature.com/articles/s41391-021-00386-5.epdf?sharing_token=CjLKgjDZrWB-m1X7d9Js_NRgN0jAjWel9jnR3ZoTv0P7jELUyNr219Zq4kRq5H298bXF-IJsH-cj1JlyD7JDx94fWpTnkwe6IkV7Lb-v1yO07Yf7cu2TSadEgjl2LgZ_Y_DmLWEs1h37trt2vZgcZNW6VI8LR0uk0Kfj1G2vE_M%3D

The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer - Prostate Cancer and Prostatic Diseases After long-term androgen deprivation therapy, 25–30% prostate cancer (PCa) acquires an aggressive neuroendocrine (NE) phenotype. Dysregulation of YAP1, a key transcription coactivator of the Hippo pathway, has been related to cancer progression. However, its role in neuroendocrine prostate cancer ...

Photos from LSU Health Shreveport School of Graduate Studies's post 08/10/2021

Students with the LSUHS School of Graduate Studies safely gathered on Friday afternoon to create a colorful fashion statement. Graduate Student Council hosted the lab coat tie-dye outside the Student Union. In addition to fresh air, games, and refreshments, the event provided students and faculty with a relaxing creative outlet. Dr. Chris Kevil, Vice Chancellor for Research and Dean of the School of Graduate Studies stopped by to craft a custom lab coat with students. COVID-19 safety precautions were in place for this outdoor student event.

Timeline Photos 08/09/2021

Timeline Photos

HAVE A QUESTION? WE'RE GETTING ANSWERS: Dr. John Vanchiere will take your COVID-19 questions and answer them tonight on live television. Submit your question here » https://bit.ly/3lMvew7

08/09/2021

Siyuan's dissertation project is titled, "The epigenetic changes involved in neuroendocrine prostate cancer development".
Here is how he describes his project:
"Prostate cancer is the most commonly diagnosed cancer type among man in United States. The androgen targeting therapy as the golden standard treatment is almost promised to fail eventually. Prostate cancer with neuroendocrine phenotype represents around 30 percent of the drug resistant cases. Unfortunately this untreatable disease is under studied. In our research, we are focusing on the developmental process of neuroendocrine prostate cancer. We first use comprehensive transcriptome analysis to identify the differentially expressed genes between neuroendocrine prostate cancer and adenocarcinoma. Based on the bioinformatics result, we then confirmed the YAP1 expression is decreased in neuroendocrine compare to adenocarcinoma in both RNA and protein level. We then found the decreased YAP1 can promote the canonical Wnt signaling in prostate cancer cells."

Siyuan's dissertation project is titled, "The epigenetic changes involved in neuroendocrine prostate cancer development".
Here is how he describes his project:
"Prostate cancer is the most commonly diagnosed cancer type among man in United States. The androgen targeting therapy as the golden standard treatment is almost promised to fail eventually. Prostate cancer with neuroendocrine phenotype represents around 30 percent of the drug resistant cases. Unfortunately this untreatable disease is under studied. In our research, we are focusing on the developmental process of neuroendocrine prostate cancer. We first use comprehensive transcriptome analysis to identify the differentially expressed genes between neuroendocrine prostate cancer and adenocarcinoma. Based on the bioinformatics result, we then confirmed the YAP1 expression is decreased in neuroendocrine compare to adenocarcinoma in both RNA and protein level. We then found the decreased YAP1 can promote the canonical Wnt signaling in prostate cancer cells."

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Fall 2022 Applications

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1501 Kings Highway
Shreveport, LA
71103

General information

Degree Offerings: Biochemistry & Molecular Biology, Ph.D. Cellular Biology & Anatomy, Ph.D. Microbiology & Immunology, Ph.D. Molecular & Cellular Physiology, Ph.D. Pharmacology, Toxicology, & Neuroscience, Ph.D. Master of Biomedical Science, M.S. M.D./Ph.D Program Combined Degree Program, M.D./Ph.D. with Louisiana Tech University
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